Adsorption Resins Apply
Macroporous
adsorption resin is type of intersectant polymer without ion
exchange. It doesn’t dissolve in any acid, alkali, organic
solvent and heated up because of intersectant solid structure.
And make it high mechanical stabilization as its flexible
structure, and high intersectant make it producing chemical. So
when it is being in inclement condition, it has higher
stabilization of physical and chemical property than gelable
resin. The hot weightlessness temperature is 266℃.
It has excellent heat-resistant and irradiate-resistant
property, and its temperature is 150℃ or so for polystyrene
resin, it can endure 200℃-250℃
in short time. It mustn’t consider of inorganic salt, strong
ion minimum-molecule compound for organic matter concentration.
It has adsorption as FanDeHua gravitation and hydrogenolysis,
and has filtration property as its multi holes structure and
huge ratio surface, so it is a extraction material that is a
compound adsorption and filtration property what is different
from ion exchange resin. Its chemical structure has or hasn’t
function radicel with different polarity. It includes
un-polarity, mid-polarity, polarity and strong polarity
according to the surface property of resin.
Macroporous adsorption resin is
widely used in environment protection﹑metallurgy
industry﹑chemical industry﹑manufacture
medicine﹑health department and etc,
especially for biochemical products﹑natural
products extraction and purification﹑medicines
preparation﹑organic compound extraction﹑chemical
reaction catalyzer﹑carrier and etc because of its own
component and construction show the character of adsorption and
sifting in extraction and purification.
Macroporous
adsorption resin is also widely used in the treatment of
industrial waste water or waste liquid. It has very good effect
in absorbing, recovery and purifying of benzene nitrobenzene﹑chlorobenzene
﹑fluorinbenzene ﹑phenol
and so on organic compound. It has high adaptability to density
of harmful ingredients in just one process. It makes it possible
to recycle and repeat use the harmful substance in industrial
production, and makes the harmful into useful and changes wastes
into treasure.
In recent years,
macroporous adsorption resin is widely used in microorganism
manufacture medicine in extraction and purification. New
antibiotic published in overseas contain almost all kinds of
compound with different composes, all that use macroporous
adsorption resin as the way for active matter in extraction.
Some antibiotic what belongs weak or non﹣ion exchange can’t
be extracted in the way of ion exchange, but now macroporous
adsorption resin can be tried to use for it. That can provide a
new way for antibiotic in purification.
It is still the most active part
for the reaction macromolecule technology field development. The
practice show that it can provide stronger adsorbing ability ﹑easy
rinse﹑high mechanical strength﹑strong
pollution-resistance that natural adsorption. Especially that
can control and choose man-made arbitrarily for the aperture﹑oppose
surface area﹑polarity and so on. So it provide
that very important way for microorganism manufacture medicine
in extraction﹑concerntration﹑purification
and so on, and make up the shortage of ion exchange instead of
classic adsorption such as active charcoal and AL203 and etc.
Macroporous adsorption resin is
widely used in medicine manufacturing and in extraction of
active ingredients in natural plants such as glycosides, flavone
, alkaloid etc. what belong to macromolecule chemical compound,
it works well in the extraction of ginsenosides ,gypenosides,saponin
on diosgenin,seviosides, liquorice P.E., Ginkgo Biloba leaf
P.E., hawthorn leaves P.E., Astraglus extract, orange skin P.E.,
epimediosides,Pueraria Poot P.E. soybean biochanin, polyphenols
, notoginsenosides, orange extract, yew P.E. various natural
pigments, Chinese medicine compound. It also has very good
result in the purification, separation, and recovery of
biochemistry medicine making. It is also widely used in
antibiotic , vitamin, amino acid, protein purification and
biochemical medicine and etc.
The
recommended condition of operation
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Process
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Flow
speed
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Flow
volume
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Remark
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fill
in poles
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|
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Fill in poles with water, the high of resin is below
3 meters
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Backwash
poles
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|
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Wipe off granule and tattered resin
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Pre-treatment
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1-5BV/h
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3BV
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Pre-treatment with ethanol
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adsorption
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1-4BV/h
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According
to adsorption
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Below capacity of adsorption, PH=5-8, temperature is
below 50℃.
|
|
washing
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2-3BV/h
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0.5-1BV
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Washing out the impurity of adsorption on resin
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desorption
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0.5-3BV/h
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2-3BV/h
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Virtual component of ethanol and acetone is
dissolved out. The temperature is fit to desorption.
|
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regeneration
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0.5-3BV/h
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3-4BV/h
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Acidity and alkaline regeneration, ethanol and
acetone is used to wash.
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washing
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2-3BV/h
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3-4BV/h
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Wash clearly with a lot of water.
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Specific property and usage of
macroporous adsorption resin
(1)
Water content of the resin is about 70%. It should be stored
in a temperature over 0℃ in wet state. Avoid frozen
breakage of ball body.
(2)
Its physical chemical property is stabled. It does not
dissolve in acid, alkali and organic solvent, indissolubility,
hot weightlessness temperature 266℃.
(3)
Before it is used the resin should be pre-treated accordingly
depending on application purpose. That is to eliminate through
infiltration the inertia solvent remains inside the resin holes.
The pre-treatment method is to add as much ethanol as to a level
10cm above the resin layer in the extraction vessel and
infiltrate 4hours before rinsed by ethanol. The rinse should be
made to a extent that the flowed out liquid becomes non-cloudy
when water diluted in test tube. Then wash it repeatedly by
water to an extent that ethanol content less than 1% or there is
no obvious ethanol smell. Then it can be used in productions.
The medical grade resin of our factory has undergone deep
treatment. So it can be used directly in productions.
(4)
In production, we suggest fill in 2 meters high of resin, and
make adsorbing flow speed 4-10 meters/h (1-4BV/h), methanol,
acetone can desorption.
(5)
Resin regenerate: after a period of using, the resin will
become weak in its adsorbing ability and maybe contaminated. So
it needs regenerate. The method is to add 3%-5% hydrochloric
acid solution to a level 10cm above resin layer in the vessel
and infiltrate for 2-4 hours, and then resin rinsed. Then use
same density hydrochloric acid solution of the quantity 3-4
times that of resin to rinsed and then wash with clear water to
an extent near neural. Then infiltrate with 3%-5% sodium
hydroxide solution for 4 hours. Then rinse. Using same density
sodium hydroxide solution of the quantity 3-4 times that of
resin volume rinse. Finally wash with clear water approach to an
extent that PH become neutral.
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